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9.2

318 reviews

Residence Inn By Marriott Jacksonville-Mayo Clinic Area

Residence Inn By Marriott Jacksonville-Mayo Clinic Area

4905 San Pablo Road South, Jacksonville, 32224, Florida, United States

Choose dates to view prices

Free parking

Outdoor swimming pool

Business center

Free wifi

Fitness center

Free shuttle

Streaming service (like Netflix)

Air conditioning

Residence Inn By Marriott Jacksonville-Mayo Clinic Area

Residence Inn by Marriott Jacksonville-Mayo Clinic Area is a 3-star hotel in Jacksonville, Florida. Located at 4905 San Pablo Road South, the property sits about 14.1mi from downtown Jacksonville. Minimum price starts from $188 per night, and the property has 318 reviews to help with planning.

Guest perks include free on-site parking, free Wifi, and an outdoor swimming pool, along with a free shuttle service and a business center. Breakfast is offered on site, and in-room comforts include a kitchen, kitchenware, air conditioning, free toiletries, a bathtub, non-smoking rooms, and wheelchair accessibility, with elevator access as needed. Streaming service options (like Netflix), a bar, terrace, picnic area, and a kid-friendly buffet add extra touches; pets are welcome with extra charges.

Ready to explore Jacksonville from a comfortable base, with plenty of amenities at hand to suit both relaxing days and busy itineraries.

An outdoor heated pool reserved for adults provides a year-round sun-soaked retreat after a day of exploring Jacksonville. A complimentary shuttle makes it easy to reach nearby sights, and free on-site parking takes the edge off travel logistics. A business center and reliable Wifi help keep plans on track, whether navigating meetings or mapping out the next neighborhood to explore.

Breakfast is served on site to jump-start mornings, and in-room comforts include a kitchen with kitchenware, air conditioning, a bathtub, free toiletries, and non-smoking rooms. Elevator access is available, making it simple to move between floors after a busy day on the town.

Pet lovers will be glad to know that pets are welcome, with charges may apply. To add a touch of extra fun, streaming service options (like Netflix), a bar, terrace, picnic area, and a kid-friendly buffet round out the experience, creating a playful balance of relaxation and discovery for all ages.

Closest airports

Jacksonville, Naval Air Station

14.6mi

Northeast Florida Regional Airport

21.3mi

Jacksonville International Airport

22.1mi

Most popular amenities

Free parking

Outdoor swimming pool

Business center

Free wifi

Fitness center

Free shuttle

Streaming service (like Netflix)

Air conditioning

Kid-friendly buffet

Bar

Parking On Site

Terrace

24-hour front desk

Kitchen

Non-smoking rooms

Wheelchair accessible

Beach chairs/Loungers

Kitchenware

Elevator

Picnic area

Upper floors accessible by elevator

Free toiletries

Bathtub

Rooms

King Studio Suite with Sofa Bed and Adapted Tub - Mobility Accessible in Residence Inn By Marriott Jacksonville-Mayo Clinic Area

Show 8 photos

Studio Suite, Accessible, Sofa

1 King Size Bed

1 Sofa Bed

410 sqft

Kitchen

Private Bathroom

Bathtub

Kitchenware

+

More details

Featuring free toiletries, this suite includes a private bathroom with a bath and a hairdryer. Guests can make meals in the kitchen that features a stovetop, a refrigerator, a dishwasher and kitchenware. The suite has carpeted floors, a seating area with a flat-screen TV with streaming services, air conditioning, a tea and coffee maker, as well as a dining area.

King Studio Suite with Sofa Bed in Residence Inn By Marriott Jacksonville-Mayo Clinic Area

Show 8 photos

Studio Suite, Sofa

1 King Size Bed

1 Sofa Bed

410 sqft

Kitchen

Private Bathroom

Bathtub

Kitchenware

+

More details

Providing free toiletries, this suite includes a private bathroom with a bath and a hairdryer. Meals can be prepared in the well-fitted kitchen, which comes with a stovetop, a refrigerator, a dishwasher and kitchenware. The suite features carpeted floors, a seating area with a flat-screen TV with streaming services, air conditioning, a tea and coffee maker, as well as a dining area.

Queen Corner Suite in Residence Inn By Marriott Jacksonville-Mayo Clinic Area

Show 8 photos

Corner Suite

2 Queen Size Beds

645 sqft

Kitchen

Private Bathroom

Bathtub

Kitchenware

+

More details

Featuring free toiletries, this suite includes a private bathroom with a bath, a shower and a hairdryer. Guests can make meals in the kitchen that features a stovetop, a refrigerator, a dishwasher and kitchenware. The spacious suite features air conditioning, a tea and coffee maker, a seating area, a dining area, as well as a flat-screen TV with streaming services.

One-Bedroom Queen Suite with Adapted Tub - Mobility Accessible in Residence Inn By Marriott Jacksonville-Mayo Clinic Area

Show 6 photos

Suite, Queen Size, Accessible, 1 Bedroom

2 Queen Size Beds

560 sqft

Kitchen

Private Bathroom

Bathtub

Kitchenware

x8

+

x5

More details

Offering free toiletries, this suite includes a private bathroom with a bath and a hairdryer. In the well-fitted kitchen, guests will find a stovetop, a refrigerator, a dishwasher and kitchenware. The spacious suite offers air conditioning, a tea and coffee maker, a seating area, a dining area, as well as a flat-screen TV with streaming services.

One-Bedroom Corner Suite with Adapted Tub - Mobility Accessible in Residence Inn By Marriott Jacksonville-Mayo Clinic Area

Show 6 photos

Corner Suite, Accessible, 1 Bedroom

1 Double Bed

645 sqft

Kitchen

Private Bathroom

Bathtub

Kitchenware

+

More details

Offering free toiletries, this suite includes a private bathroom with a bath and a hairdryer. Guests can make meals in the kitchen that is fitted with a stovetop, a refrigerator, a dishwasher and kitchenware. The spacious air-conditioned suite offers a flat-screen TV with streaming services, a tea and coffee maker, a seating area and a dining area.

Queen Suite with  2 Queen, Sofa bed in Residence Inn By Marriott Jacksonville-Mayo Clinic Area

Show 8 photos

Suite, 2 Queen Size Beds, 1 Bedroom

1 Sofa Bed

2 Queen Size Beds

560 sqft

Kitchen

Private Bathroom

Bathtub

Kitchenware

x8

+

x5

More details

Providing free toiletries, this suite includes a private bathroom with a bath, a shower and a hairdryer. In the fully equipped kitchen, guests will find a stovetop, a refrigerator, a dishwasher and kitchenware. The spacious suite provides air conditioning, a tea and coffee maker, a seating area, a dining area and a flat-screen TV with streaming services.

King Corner Studio Suite, with Sofa bed in Residence Inn By Marriott Jacksonville-Mayo Clinic Area

Show 4 photos

Corner Studio Suite, Sofa

1 King Size Bed

1 Sofa Bed

540 sqft

Kitchen

Private Bathroom

Bathtub

Kitchenware

+

More details

Providing free toiletries, this suite includes a private bathroom with a bath and a hairdryer. Guests can make meals in the kitchen that comes with a stovetop, a refrigerator, a dishwasher and kitchenware. The suite features carpeted floors, a seating area with a flat-screen TV with streaming services, air conditioning, a tea and coffee maker, as well as a dining area.

Room

Show 11 photos

Studio, Accessible

1 King Size Bed

+

More details

Show 7 photos

Corner Suite, 1 Bedroom, Sofa

2 Queen Size Beds

1 Sofa Bed

More details

Show 4 photos

Studio Corner, King Size, Accessible, Sofa

1 King Size Bed

1 Sofa Bed

+

More details

The unit has 2 beds.

Suite, Queen Size, 1 Bedroom, Sofa

1 Queen Size Bed

1 Sofa Bed

Free wifi

Microwave

Flat-screen TV

x8

+

x5

More details

Room

Show 16 photos

Studio

1 King Size Bed

+

More details

Guest reviews

9.2

318 reviews

Categories of assessments

Cleanliness

Comfort

Location

Facilities

Staff

Value for money

WiFi quality

Breakfast

Featured reviews:

🇺🇸

Kimberly

10

March 2025

The staff were incredibly friendly, accommodating, and knowledgable. They went above and beyond to make sure I had a pleasant stay. I am a patient at Mayo Clinic, so the location is perfect and the free shuttle service to Mayo is a wonderful amenity and gives me peace of mind. The hotel is also within walking distance of Mayo. Even if you're not a patient at Mayo, the Residence Inn is a great central location for whatever brings you to Jacksonville. The complimentary breakfast is great, with many healthy options. One of the best.

I have no complaints.

🇺🇸

Kimberly

10

February 2025

I love the kitchenettes because I enjoy cooking my meals, so I don't usually have the breakfast but it looks great. The staff is particularly helpful and positive. The close location to Mayo Clinic is key for me. The free hourly shuttle is perfect and it's even close enough to walk, .8 miles.

Can't think of anything I didn't like.

🇺🇸

Evangeline

10

January 2023

The bed was so comfortable! I liked the fact that every room is a suite as well. There was an ice machine on every floor and a small kitchen with a dishwasher, two burner range, microwave, and a regular sized refrigerator. My room also had a dedicated work space with a built in outlet to charge your devices, a desk lamp, and a comfortable chair. The TV was nice and it swiveled so it could be viewed from the bed or in the common area(a mini-living room). In addition, there is a shuttle that transports you to and from the Mayo Clinic free of charge.

It's very expensive, but there are lots of conveniences. The phone signal was horrible. I have Verizon and apparently, there isn't a tower close by. The signal in my room was better, but down in the lobby, it was non-existent.

🇺🇸

Sherese

9.1

June 2023

The bed was comfortable and the room was spacious. The breakfast was ok. The eggs were different. They were cheese omelet. They tasted pretty good.

The breakfast was ok. There was only sausage and no bacon. Not a large selection to choose from in that format. Just the cheese omelet, sausage, and biscuit with gravy as far as that goes, no grits, bacon, or scrambled eggs. My phone was not able to make any outside calls or connect unless you use the hotel's wifi. I can usually use my phone's connection and not have to use the hotel's wifi.

🇺🇸

Shelly

10

March 2024

The room was nice clean comfortable. Free breakfast was great! Mayo Clinic shuttle services were free. Nice sitting areas indoor and especially outdoor.

Maybe start breakfast at 6 am vs 6:30. Otherwise everything was great. No complaints!

🇺🇸

Jane

8.2

January 2024

Close to the Mayo Clinic, provided breakfast in a nice setting. Liked having a kitchen in the room and a desk area. My husband worked while I attended appointments.

Internet was terrible, very slow so made it difficuit for my husband to get work done. The clean dishes from the previous guest were left in the dishwasher and not put away.

🇺🇸

Marcus

8.2

September 2023

No room service on the 2nd night stay??? Sign (door sign for no service) was taken down from the first night. Hose keeping cleary had come into the room because there were fresh towels and new soap, BUT THAT WAS ALL THAT WAS DONE! This was entirely unexpected. Wanted a clean room to come back on the second day and that did not happen.

🇺🇸

Catherine

9.1

February 2025

Excellent breakfast offerings and it is why we will make another reservation. We also had dinner at the bar and the food and service was amazing! Thank you!

Wish we could have stayed longer to take advantage of the gym and pool!

🇺🇸

Christina

10

November 2023

Spacious rooms, welcoming staff. Grounds were beautifully kept with lush trees, pond area in back, and trails to walk. Location was next to Mayo Clinic, and also provides shuttle service to and from. Full bar and restaurant, hot buffet breakfast.

As a wheelchair user, kitchen cabinets were out of reach.

🇺🇸

Lorraine

10

June 2023

King corner suite was very livable. Usable kitchen with large refrigerator, microwave and stovetop with 2 burners. Pots, pans dishes and utensils were provided. Large room with big windows. Bed and pillows were clean and comfortable.

No Keurig coffee maker. I like to bring my preference of flavored k-cups. Hotel coffee I found to be weak.

Points of Interest Around Residence Inn By Marriott Jacksonville-Mayo Clinic Area

Airports

Jacksonville, Naval Air Station

14.6mi

Northeast Florida Regional Airport

21.3mi

Jacksonville International Airport

22.1mi

Pools

Location

  • Outdoor

Features

  • Heated

Age restrictions

  • Adults only

Availability

  • All season

Amenities of Residence Inn By Marriott Jacksonville-Mayo Clinic Area

Free parking

Outdoor swimming pool

Business center

Free wifi

Fitness center

Free shuttle

Streaming service (like Netflix)

Air conditioning

Kid-friendly buffet

Bar

Parking On Site

Terrace

24-hour front desk

Kitchen

Non-smoking rooms

Wheelchair accessible

Beach chairs/Loungers

Kitchenware

Elevator

Picnic area

Upper floors accessible by elevator

Free toiletries

Bathtub

Stay rules - Residence Inn By Marriott Jacksonville-Mayo Clinic Area

  • Check-in / Check-out

  • Pets

  • Internet

  • Age restrictions

  • Curfew

  • Parking

  • Children and beds

  • Cards accepted at this property

Frequently Asked Questions - Residence Inn By Marriott Jacksonville-Mayo Clinic Area

Can pets stay with guests at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?

Yes, you can stay with your pet at Residence Inn By Marriott Jacksonville-Mayo Clinic Area. However, please note that charges may apply for bringing your pet along.

What are the check-in and check-out times at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?

For those planning to reside at Residence Inn By Marriott Jacksonville-Mayo Clinic Area, the doors open for check-in at 04:00 PM and it's time to say goodbye by 11:00 AM.

Does Residence Inn By Marriott Jacksonville-Mayo Clinic Area come with parking?

Yes, there is parking available at the Residence Inn By Marriott Jacksonville-Mayo Clinic Area. It is free and located on site. It is public parking, and no reservation is required.

How much does a stay at Residence Inn By Marriott Jacksonville-Mayo Clinic Area cost?

A stay at Residence Inn By Marriott Jacksonville-Mayo Clinic Area can begin from a rate of $188. This is subject to change based on room selection and travel dates. For a clear price, input your desired stay dates.

Which room categories can I book at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?

The hotel offers a variety of suites with different sizes and bed configurations. They have King Studio Suites with one King size bed and a Sofa Bed, Queen Corner Suites with two Queen size beds, and One-Bedroom Queen Suites with two Queen size beds. The rooms vary in size, ranging from 409 sqft to 646 sqft. Smoking is not allowed in any of the rooms. The suites can accommodate between 3 adults and 2 children to 5 adults and 4 children.

Which amenities can guests enjoy at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?

At Residence Inn By Marriott Jacksonville-Mayo Clinic Area, guests have several leisure amenities to enjoy. One of the highlights is the outdoor swimming pool, available all season. This pool provides a refreshing place for guests to relax and cool off. The hotel also offers beach chairs and loungers for guests to use, adding to their poolside comfort.

Additionally, guests can take advantage of the hotel's other amenities to enhance their leisure time. They can enjoy a round of golf at the nearby golf course or soak up the sun on the sun deck. For those who prefer indoor activities, the fitness center is available for workouts. The hotel also provides board games and puzzles for those looking for some indoor entertainment.

In summary, guests at the Residence Inn By Marriott Jacksonville-Mayo Clinic Area can spend their time enjoying the outdoor swimming pool, lounging on beach chairs, playing golf, working out in the fitness center, or relaxing on the sun deck.

Is there a swimming pool at Residence Inn By Marriott Jacksonville-Mayo Clinic Area?

The Residence Inn By Marriott Jacksonville-Mayo Clinic Area has one pool available. It is an outdoor pool that is open all year round. However, there are age restrictions in place, as it is only for adults.

Does Residence Inn By Marriott Jacksonville-Mayo Clinic Area accept credit cards?

Residence Inn By Marriott Jacksonville-Mayo Clinic Area does not accept cash as a payment method. However, they do accept credit cards such as Discover, Mastercard, JCB, Visa, and American Express.

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